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journal of men's health
Volume 5, Issue 4
, Pages 342-349
, December 2008
Treatment for late-onset hypogonadism: the current situation in Japan
References
- . Low serum testosterone and mortality in male veterans. Arch Intern Med. 2006;166:1660–1665
- . Investigation, treatment and monitoring of late-onset hypogonadism in males. Official recommendations of ISSAM: International Society for the Study of the Aging Male. Aging Male. 2002;5:74–86
- Investigation, treatment and monitoring of late-onset hypogonadism in males. ISA, ISSAM, and EAU recommendations. Eur Urol. 2005;48:1–4
- . Androgens and aging. Maturitas. 2001;38:61–71discussion 71–3
- Endocrine aspects of sexual dysfunction in men. J Sex Med. 2004;1:69–81
- . Androgen deficiency in aging men. Med Clin North Am. 1999;83:1279–1289vii.
- . Andropause. Maturitas. 2000;34:5–15
- . Andropause: a misnomer for a true clinical entity. J Urol. 2000;163:705–712
- Bioavailable testosterone with age and erectile dysfunction. J Urol. 2003;170:2345–2347
- Clinical practice manual for late-onset hypogonadism syndrome. Int J Urol. 2008;15:377–388
- . Sexual function with advancing age. Med Clin North Am. 1989;73:1483–1495
- . Hormonal changes and sexual function in aging men. J Clin Endocrinol Metab. 1983;57:71–77
- . Testosterone and erectile function, nocturnal penile tumescence and rigidity, and erectile response to visual erotic stimuli in hypogonadal and eugonadal men. Psychoneuroendocrinology. 1992;17:647–654
- . The clinical relevance of sex hormone levels and sexual activity in the ageing male. BJU Int. 2002;89:526–530
- . Changes in erectile responsiveness during androgen replacement therapy. Arch Sex Behav. 1983;12:59–66
- . Effects of androgen on sexual behavior in hypogonadal men. J Clin Endocrinol Metab. 1979;48:955–958
- . Outcomes of long-term testosterone replacement in older hypogonadal males: a retrospective analysis. J Clin Endocrinol Metab. 1997;82:3793–3796
- . The effects of transdermal dihydrotestosterone in the aging male: a prospective, randomized, double blind study. J Clin Endocrinol Metab. 2002;87:1467–1472
- . The nature of androgen action on male sexuality: a combined laboratory-self-report study on hypogonadal men. J Clin Endocrinol Metab. 1983;57:557–562
- . Combined use of androgen and sildenafil for hypogonadal patients unresponsive to sildenafil alone. Int J Impot Res. 2006;18:400–404
- . Sexuality and disease. Clin Geriatr Med. 2003;19:563–573
- . A long-term, prospective study of the physiologic and behavioral effects of hormone replacement in untreated hypogonadal men. J Androl. 1992;13:297–304
- . Follow-up of 30 Klinefelter males treated with testosterone. Clin Genet. 1988;33:262–269
- . Risks versus benefits of testosterone therapy in elderly men. Drugs Aging. 1999;15:131–142
- . Bioavailable testosterone and depressed mood in older men: the Rancho Bernardo Study. J Clin Endocrinol Metab. 1999;84:573–577
- Testosterone replacement therapy improves mood in hypogonadal men – a clinical research center study. J Clin Endocrinol Metab. 1996;81:3578–3583
- Effect of testosterone supplementation on functional mobility, cognition, and other parameters in older men: a randomized controlled trial. JAMA. 2008;299:39–52
- DHEA in elderly women and DHEA or testosterone in elderly men. N Engl J Med. 2006;355:1647–1659
- . A double-blind, placebo-controlled trial of testosterone therapy for HIV-positive men with hypogonadal symptoms. Arch Gen Psychiatry. 2000;57:141–147discussion 55–6
- . Testosterone therapy for human immunodeficiency virus-positive men with and without hypogonadism. J Clin Psychopharmacol. 1999;19:19–27
- . Marked disparity between trabecular and cortical bone loss with age in healthy men. Measurement by vertebral computed tomography and radial photon absorptiometry. Ann Intern Med. 1984;101:605–612
- . The rate of bone mineral loss in normal men and the effects of calcium and cholecalciferol supplementation. Ann Intern Med. 1990;112:29–34
- . Differential changes in bone mineral density of the appendicular and axial skeleton with aging: relationship to spinal osteoporosis. J Clin Invest. 1981;67:328–335
- . Endogenous sex steroids and bone mineral density in older women and men: the Rancho Bernardo Study. J Bone Miner Res. 1997;12:1833–1843
- . Relationship of serum sex steroid levels to longitudinal changes in bone density in young versus elderly men. J Clin Endocrinol Metab. 2001;86:3555–3561
- . Relationship of serum sex steroid levels and bone turnover markers with bone mineral density in men and women: a key role for bioavailable estrogen. J Clin Endocrinol Metab. 1998;83:2266–2274
- . Male osteopenia: a brief review. J Am Geriatr Soc. 1987;35:258–261
- . Risk factors for spinal osteoporosis in men. Am J Med. 1983;75:977–983
- . Changes in plasma steroids and bone density in Klinefelter's syndrome. Calcif Tissue Res. 1977;22(Suppl):225–228
- . Testosterone deficiency as a risk factor for hip fractures in men: a case-control study. Am J Med Sci. 1992;304:4–8
- Dehydroepiandrosterone (DHEA), DHEA sulfate, and aging: contribution of the DHEAge Study to a sociobiomedical issue. Proc Natl Acad Sci USA. 2000;97:4279–4284
- . Long-term substitution therapy of hypogonadal men with transscrotal testosterone over 7–10 years. Clin Endocrinol (Oxf). 1999;50:629–635
- . Effects of transdermal testosterone on bone and muscle in older men with low bioavailable testosterone levels. J Gerontol A Biol Sci Med Sci. 2001;56:M266–M272
- . Testosterone replacement in older hypogonadal men: a 12-month randomized controlled trial. J Clin Endocrinol Metab. 1997;82:1661–1667
- Effect of testosterone treatment on bone mineral density in men over 65 years of age. J Clin Endocrinol Metab. 1999;84:1966–1972
- Effects of testosterone replacement in hypogonadal men. J Clin Endocrinol Metab. 2000;85:2670–2677
- . Adult lean body mass declines with age: some longitudinal observations. Metabolism. 1970;19:653–663
- . The role of muscle loss in the age-related decline of grip strength: cross-sectional and longitudinal perspectives. J Gerontol. 1990;45:M82–M88
- . Studies in the distribution of body fat: I. Effects of age, sex, and obesity. J Gerontol. 1989;44:M66–73
- . Predictors of skeletal muscle mass in elderly men and women. Mech Ageing Dev. 1999;107:123–136
- Predictors of lean body mass and total adipose mass in community-dwelling elderly men and women. Am J Med Sci. 1998;315:188–193
- Testosterone administration to older men improves muscle function: molecular and physiological mechanisms. Am J Physiol Endocrinol Metab. 2002;282:E601–E607
- . Effects of testosterone replacement on muscle mass and muscle protein synthesis in hypogonadal men – a clinical research center study. J Clin Endocrinol Metab. 1996;81:3469–3475
- . AA2500 testosterone gel normalizes androgen levels in aging males with improvements in body composition and sexual function. J Clin Endocrinol Metab. 2003;88:2673–2681
- Sublingual testosterone replacement improves muscle mass and strength, decreases bone resorption, and increases bone formation markers in hypogonadal men – a clinical research center study. J Clin Endocrinol Metab. 1996;81:3654–3662
- . Oral testosterone supplementation increases muscle and decreases fat mass in healthy elderly males with low-normal gonadal status. J Gerontol A Biol Sci Med Sci. 2003;58:618–625
- . Loss of bone mass in patients with Klinefelter's syndrome despite sufficient testosterone replacement. Osteoporos Int. 1993;3:3–7
- . Physiologic mechanisms and the hematopoietic effects of the androstanes and their derivatives. Curr Top Hematol. 1983;4:123–195
- . Increased erythropoiesis induced by androgenic-hormone therapy. N Engl J Med. 1957;256:719–726
- Treatment with human chorionic gonadotropin for PADAM: a preliminary report. Aging Male. 2005;8:175–179
- . Effects of testosterone supplementation in the aging male. J Clin Endocrinol Metab. 1992;75:1092–1098
- Effect of testosterone replacement therapy on prostate tissue in men with late-onset hypogonadism: a randomized controlled trial. JAMA. 2006;296:2351–2361
- . Beneficial effects of testosterone administration on symptoms of the lower urinary tract in men with late-onset hypogonadism: a pilot study. Aging Male. 2008;11:57–61
- Androgen treatment of abdominally obese men. Obes Res. 1993;1:245–251
- Is discontinuation of hormone replacement therapy possible for patients with late-onset hypogonadism?. Int J Urol. 2008;15(7):625–629
- . Testosterone therapy for men at risk for or with history of prostate cancer. Curr Treat Options Oncol. 2006;7:363–369
- . Testosterone and prostate cancer: an historical perspective on a modern myth. Eur Urol. 2006;50:935–939
- . Testosterone supplementation for hypogonadal impotence: assessment of biochemical measures and therapeutic outcomes. J Urol. 1997;157:849–854
- Intramuscular testosterone undecanoate: pharmacokinetic aspects of a novel testosterone formulation during long-term treatment of men with hypogonadism. J Clin Endocrinol Metab. 2004;89:5429–5434
- . Improvement of sexual function in men with late-onset hypogonadism treated with testosterone only. J Sex Med. 2007;4:497–501
- . Pharmacokinetics, efficacy, and safety of a permeation-enhanced testosterone transdermal system in comparison with bi-weekly injections of testosterone enanthate for the treatment of hypogonadal men. J Clin Endocrinol Metab. 1999;84:3469–3478
- . Comparison of testosterone, dihydrotestosterone, luteinizing hormone, and follicle-stimulating hormone in serum after injection of testosterone enanthate or testosterone cypionate. Fertil Steril. 1980;33:201–203
- . Diurnal rhythm of testosterone induced by human chorionic gonadotrophin (hCG) therapy in isolated hypogonadotrophic hypogonadism: a comparison between subcutaneous and intramuscular hCG administration. Eur J Endocrinol. 1994;131:173–178
- . Stimulation of spermatogenesis by gonadotropins in men with hypogonadotropic hypogonadism. N Engl J Med. 1985;313:651–655
- . Predicting pregnancy and spermatogenesis by survival analysis during gonadotrophin treatment of gonadotrophin-deficient infertile men. Hum Reprod. 2002;17:625–633
- . Human chorionic gonadotrophin therapy in male infertility. JAMA. 1977;237:2423
- . Combined hMG/hCG treatment in subfertile men with idiopathic normogonadotrophic oligozoospermia. Int J Androl. 1982;5:467–477
- Profile of serum testosterone levels after application of testosterone ointment (glowmin) and its clinical efficacy in late-onset hypogonadism patients. J Sex Med. 2008;5(7):1727–1736
- . Andropause: hormone replacement therapy in the ageing male. Eur Urol. 2000;38:655–662
- . Testosterone replacement and the physiologic aspects of aging in men. Mayo Clin Proc. 2000;75(Suppl):S83–S87
- . Androgen treatment of male hypogonadism in older males. J Steroid Biochem Mol Biol. 2003;85:367–373
- . Perception of males’ aging symptoms, health and well-being in elderly community-dwelling men is not related to circulating androgen levels. Psychoneuroendocrinology. 2004;29:201–214
- . Self-referred patients in an aging male clinic: much more than androgen deficiency alone. Aging Male. 2003;6:157–165
- Comparative study on evaluation methods for serum testosterone level for PADAM diagnosis. Int J Impot Res. 2005;17:259–263
- . Correlation between the Aging Males’ Symptoms Scale and sex steroids, gonadotropins, dehydroepiandrosterone sulfate, and growth hormone levels in ambulatory men. J Sex Med. 2006;3:723–726
- Prevalence of symptomatic androgen deficiency in men. J Clin Endocrinol Metab. 2007;92:4241–4247
- . Does the Aging Males’ Symptoms scale assess major depressive disorder?: a pilot study. Maturitas. 2006;53:171–175
- Prevalence of major depressive disorder in self-referred patients in a late onset hypogonadism clinic. Int J Impot Res. 2007;19:407–410
- . Menopausal hot flash and calciotonin gene-related peptide; effect of Keishi-bukuryo-gan, a kampo medicine, related to plasma calciotonin gene-related peptide level. Maturitas. 2003;45:199–204
- . Changes in serum tumor necrosis factor (TNF-alpha) with kami-shoyo-san administration in depressed climacteric patients. Am J Chin Med. 2004;32:621–629
- Pittler MH, Ernst E. Kava extract for treating anxiety. Cochrane Database Syst Rev 2003:CD003383.
- A randomized trial of two different doses of a SHR-5 Rhodiola rosea extract versus placebo and control of capacity for mental work. Phytomedicine. 2003;10:95–105
- . Treatment of climacteric symptoms with herbal formulas of traditional Chinese medicine. Gynecol Obstet Invest. 2004;57:144–148
- . Chai-hu-gui-zhi-gan-jiang-tang regulates plasma interleukin-6 and soluble interleukin-6 receptor concentrations and improves depressed mood in climacteric women with insomnia. Am J Chin Med. 2005;33:703–711
- Clinical trial of treatment with saikokaryukotsuboreito for eugonadal patients with late-onset hypogonadism-related symptoms. Aging Male. 2008;11:95–99
PII: S1875-6867(08)00208-X
doi: 10.1016/j.jomh.2008.10.003
© 2008 WPMH GmbH. Published by Elsevier Inc. All rights reserved.
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journal of men's health
Volume 5, Issue 4
, Pages 342-349
, December 2008
