journal of men's health
Volume 5, Issue 1 , Pages 36-41, March 2008

The Russian experience of studying vardenafil efficacy and safety in men with erectile dysfunction of various aetiologies

  • A.A. Kamalov, MD, PhD

      Affiliations

    • Russian Scientific Institute of Urology, 3rd Parkovaya St., 51, Moscow, 105425, Russia
    • Corresponding Author InformationCorresponding author.
    • ,
  • S.D. Dorofeev

      Affiliations

    • National Research Center for Urology, Russian Friendship of Peoples Department of Urology, Moscow, Russia
    • ,
  • E.A. Efremov, PhD

      Affiliations

    • Russian Scientific Institute of Urology, 3rd Parkovaya St., 51, Moscow, 105425, Russia
    • ,
  • D.A. Okhobotov

      Affiliations

    • Russian Academy of Continued Medical Education, Departments of Endoscopic Urology, Urology and Surgical Andrology, Moscow, Russia
    • ,
  • S.M. Panyushkin

      Affiliations

    • National Research Center for Roentgenology and Radiology of Russia, Russian State Medical University, Departments of Urology and Surgical Nephrology, Moscow, Russia

Abstract 

Background

Vardenafil is a first-line drug in the therapy for erectile dysfunction (ED) of various aetiologies.

Methods

An open, multi-centre study assessing the efficacy and safety of vardenafil prescribed in flexible doses for 12 weeks to men with ED from various aetiologies was performed in Moscow in 2003–2004. A total of 129 patients aged from 22 to 76 years (mean=45.7±12.9) were enrolled into the study. The efficacy of the drug was evaluated using the International Index of Erectile Function (IIEF) Questionnaire, individual patients’ diaries and the Global Assessment Questionnaire (GAQ).

Results

Scores for erectile function, maintenance of erection, satisfaction with sexual experience and satisfaction with overall sexual life all increased between the beginning and the end of this study, which has thus shown vardenafil's high efficacy and safety for patients.

Conclusion

Alongside its cardiovascular safety, one of the advantages of vardenafil is the opportunity for flexible dosing owing to the variety of dosages available.

Keywords: Vardenafil, Erectile dysfunction, PDE inhibitors

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PII: S1875-6867(08)00011-0

doi:10.1016/j.jomh.2008.01.005

journal of men's health
Volume 5, Issue 1 , Pages 36-41, March 2008

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